No different in any city. The prefex 2,3,4,5 etc. just means its a bypass route to eliminate traveling through the main part of a city. If your on 290 going around Chicago, eventually you will be back to 90. 90 is an east/west route across the country and the bypasses in every state it goes through will have a prefex to allow you to skip the city traffic. Check 75 to Florida, or 80 to California.
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